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Published on: October 12, 2012
A lupus-like reaction to subcutaneous interferon-α at injection sites
Hubert M Chodkiewicz1, Philip R Cohen, Kevin B Kim
1The University of Texas-Houston Medical School, Houston, TX, USA.
Abstract:
Interferon-α has been associated with a wide range of adverse events (AEs). A lupus-like reaction at the injection site of subcutaneous (SC) interferon-α is exceptionally rare. A 60-year-old woman with recurrent metastatic melanoma repeatedly developed cutaneous lupus-like reactions at the SC interferon-α-2b injection sites on her thighs. Known features of lupus-like reactions at SC interferon-α injection sites are reviewed, and cutaneous injection site reactions to SC interferon-α are summarized.
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