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Updated: May 24, 2026

Point-of-Care Kidney and Genitourinary Ultrasound in Adults: Image Acquisition
Published on: June 21, 2024
Postnatal imaging of neonates with prenatally diagnosed genitourinary abnormalities: a practical approach
Monica Epelman1, Teresa Victoria, Kevin E Meyers
1Department of Radiology, The Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA. epelman@email.chop.edu
Insights
Prenatal imaging advances have shifted neonatal genitourinary abnormality evaluation towards asymptomatic infants. Ultrasound (US) and fetal MRI guide imaging and surveillance, optimizing care for these neonates.
Area of Science:
- Pediatric Radiology
- Neonatal Imaging
- Genitourinary Abnormalities
Background:
- Prenatal ultrasound (US) and fetal MRI have altered referral patterns for neonatal genitourinary abnormalities.
- Most neonates evaluated for these conditions are asymptomatic, requiring multidisciplinary consultation, imaging, and surveillance.
- Reviewing prenatal studies is crucial for prognostic information and potentially avoiding repeat examinations.
Purpose of the Study:
- To discuss a practical approach to postnatal imaging of neonates with genitourinary anomalies.
- To present and illustrate important genitourinary anomalies in this age group.
Main Methods:
- Ultrasound (US) as the first-line modality for morphological assessment.
- Combination of US with MAG-3 scanning for anatomical and functional information.
- Increasing role of MRI and MR urography as comprehensive "one-stop-shop" examinations.
- Fluoroscopic examinations reserved for specific diagnostic needs like excluding vesicoureteral reflux or urethral obstruction.
Main Results:
- Prenatal imaging provides crucial prognostic information.
- US combined with MAG-3 offers both anatomical and functional data.
- MRI and MR urography provide comprehensive anatomical and functional assessment.
- Fluoroscopy aids in diagnosing specific conditions like reflux and obstruction.
Conclusions:
- Modern imaging techniques like fetal MRI and US have refined the diagnostic pathway for neonatal genitourinary anomalies.
- A systematic approach integrating various imaging modalities ensures efficient and accurate evaluation.
- Understanding the strengths of each imaging modality is key to optimizing care for neonates with genitourinary abnormalities.
Abstract:
The advent of prenatal US and, more recently, fetal MRI has changed our pattern of referrals. In the current clinical algorithms, most neonates evaluated for genitourinary abnormalities are asymptomatic. These infants are referred for multidisciplinary consultation, imaging and surveillance. Evaluation of these children commences following pertinent review of available prenatal studies; this is appropriate, as in certain instances prenatally gathered information of potential prognostic significance can be inferred or can obviate the need for multiple examinations. US remains the first-line imaging modality for diagnosing urinary abnormalities in neonates and young infants, although it offers primarily morphological assessment. However, US coupled with MAG-3 scanning results in a powerful combination that provides anatomical and functional information. Recently, MRI and MR urography have been increasingly regarded as one-stop-shop examinations that can deliver both anatomical and functional information, and play an increasing role in the evaluation of ureteral ectopia and genital anomalies. Fluoroscopic examinations are reserved to exclude vesicoureteral reflux, to delineate urethral obstruction or to provide additional information to support a diagnosis. A practical approach to postnatal imaging of the neonate is discussed and the important genitourinary anomalies in this age group are presented and illustrated.
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