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Bladder involvement in Behcet's disease
Farshid Alizadeh1, Mohammad Hatef Khorrami, Mohammad Hossein Izadpanahi
1Isfahan Urology and Renal Transplantation Research Center, Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.
Urology Journal
|March 8, 2012
Summary
Bladder involvement in Behcet
Area of Science:
- Urology
- Rheumatology
- Neurology
Background:
- Behcet's disease is a rare multisystemic inflammatory disorder.
- Bladder involvement is an uncommon but significant complication, impacting both storage and emptying functions.
- Understanding these urologic manifestations is crucial for comprehensive patient management.
Purpose of the Study:
- To comprehensively review the various aspects of bladder involvement in Behcet's disease.
- To elucidate the clinical presentation, urodynamic findings, and cystoscopic features.
- To discuss management strategies and treatment tolerance in affected patients.
Main Methods:
- Systematic literature search conducted on PubMed, Ovid, and Google Scholar.
- Keywords included Behcet's disease, neuro-Behcet's disease, neurogenic bladder, and urologic manifestations.
- Analysis of 14 full-text articles and 1 abstract focusing on bladder involvement.
Main Results:
- Predominantly affects young to middle-aged men.
- Storage symptoms (e.g., urgency, frequency) are most common, alongside emptying difficulties.
- Urodynamics often show detrusor overactivity; cystoscopy may reveal vasculitic ulcers or nodules.
- Cancer risk is not increased; surgery and chemotherapy are well-tolerated, but radiotherapy may elevate complications.
Conclusions:
- Treatment requires a personalized approach based on the specific bladder dysfunction.
- Regular monitoring is essential due to the dynamic nature of bladder involvement in Behcet's disease.
- Multidisciplinary care integrating urology, rheumatology, and neurology is recommended.
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