[Castleman disease in the pelvic retroperitoneum]

Area of Science:

• Oncology
• Pathology

Background:

• Castleman disease, first described in 1956, predominantly affects the thoracic cavity.
• Pelvic cavity involvement is exceptionally rare, with only seven previous reports.

Observation:

• A 41-year-old male presented with microscopic hematuria and a solitary pelvic retroperitoneal mass identified via imaging.
• Abnormal laboratory findings included an abnormal glucose tolerance test (GTT), elevated erythrocyte sedimentation rate, alpha 2-globulin, CRP titer, and microscopic hematuria.

Findings:

• Surgical resection of the encapsulated, 4x3x2 cm tumor confirmed the plasma cell type of Castleman disease.
• Post-operatively, most laboratory abnormalities resolved within three weeks, except for GTT and microscopic hematuria.

Implications:

• This case highlights the possibility of Castleman disease in the pelvic retroperitoneum.
• Surgical management appears effective, with the patient remaining disease-free for two years post-operation.