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Updated: May 24, 2026

Extracellular Vesicle Tissue Factor Activity Assay

Extracellular Vesicle Tissue Factor Activity Assay

Published on: December 29, 2023

Tissue factor and cardiomyocytes.

¹Charité – Universitätsmedizin Berlin, Campus Benjamin Franklin, Zentrum für Herz und Kreislaufmedizin, 12200 Berlin, Germany. ursula.rauch@charite.de

Thrombosis Research

|March 9, 2012

Summary

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Tissue factor (TF) is crucial for preventing bleeding in organs. This review explores TF

Area of Science:

Cardiovascular Biology
Hemostasis and Thrombosis
Cardiac Pathophysiology

Background:

Tissue factor (TF) initiates blood coagulation and is constitutively expressed in cardiomyocytes and fibroblasts.
Beyond hemostasis, TF is implicated in various cardiac functions.
Understanding TF's role is vital for cardiac health.

Purpose of the Study:

To review the diverse functions of tissue factor within the heart.
To emphasize the role of TF in cardiac pathological conditions.

Main Methods:

Literature review of existing studies on tissue factor in the heart.
Synthesis of information regarding TF's functions and implications in cardiac disease.

Main Results:

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Last Updated: May 24, 2026

Extracellular Vesicle Tissue Factor Activity Assay

Extracellular Vesicle Tissue Factor Activity Assay

Published on: December 29, 2023

Flow Cytometry Analysis of Tissue Factor Expression in Human Platelets

Flow Cytometry Analysis of Tissue Factor Expression in Human Platelets

Published on: November 22, 2024

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TF is essential for maintaining cardiac hemostasis.
TF influences several other critical functions within the cardiac muscle.
Pathological conditions significantly involve TF activity in the heart.

Conclusions:

Tissue factor plays a multifaceted role in the heart, extending beyond coagulation.
Further research into TF's specific functions and pathological involvement is warranted.