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Autism Spectrum Disorder

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.

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Related Experiment Video

Updated: May 24, 2026

Use of a Video Scoring Anchor for Rapid Serial Assessment of Social Communication in Toddlers

Use of a Video Scoring Anchor for Rapid Serial Assessment of Social Communication in Toddlers

Published on: March 14, 2018

Toddler autism screening questionnaire: development and potential clinical validity.

Wen-Che Tsai¹, Wei-Tsuen Soong, Yea-Ing Lotus Shyu

¹National Taiwan University Hospital, Taiwan.

Autism : the International Journal of Research and Practice

|March 9, 2012

Summary

A new autism screening questionnaire was developed for Taiwanese children. This tool shows high accuracy in identifying children at risk for autism, addressing a critical need for early detection.

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Published on: December 14, 2012

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Last Updated: May 24, 2026

Use of a Video Scoring Anchor for Rapid Serial Assessment of Social Communication in Toddlers

Use of a Video Scoring Anchor for Rapid Serial Assessment of Social Communication in Toddlers

Published on: March 14, 2018

Portable Intermodal Preferential Looking (IPL): Investigating Language Comprehension in Typically Developing Toddlers and Young Children with Autism

Portable Intermodal Preferential Looking (IPL): Investigating Language Comprehension in Typically Developing Toddlers and Young Children with Autism

Published on: December 14, 2012

Area of Science:

Developmental Psychology
Pediatric Psychiatry
Screening Tools

Background:

Existing autism screening instruments are not suitable for Taiwan's unique cultural and healthcare contexts.
There is a significant need for a culturally appropriate tool for early autism detection in Taiwanese children.

Purpose of the Study:

To develop and validate a screening questionnaire for identifying children with autism in Taiwan.
To create a reliable instrument for early autism risk detection.

Main Methods:

An 18-item questionnaire was initially developed based on expert interviews and pilot testing.
The questionnaire was refined based on item discrimination analysis (kappa >0.20), resulting in a 15-item revised version.
Receiver operating characteristic (ROC) curve analysis was used to determine optimal cutoff scores.

Main Results:

The revised 15-item questionnaire demonstrated strong psychometric properties.
Cutoff scores of 5 and 6 achieved 100% sensitivity and 96.5% specificity.
The area under the ROC curve was 0.983, indicating excellent diagnostic accuracy.

Conclusions:

The developed screening instrument is highly sensitive and specific for identifying Taiwanese children at risk for autism.
This tool has the potential to significantly improve early autism detection in Taiwan.
Further validation in a large-scale, population-based study is recommended.