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Related Concept Videos

What is Population Genetics?01:25

What is Population Genetics?

A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
Hardy-Weinberg Principle01:49

Hardy-Weinberg Principle

Diploid organisms have two alleles of each gene, one from each parent, in their somatic cells. Therefore, each individual contributes two alleles to the gene pool of the population. The gene pool of a population is the sum of every allele of all genes within that population and has some degree of variation. Genetic variation is typically expressed as a relative frequency, which is the percentage of the total population that has a given allele, genotype or phenotype.

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Updated: May 24, 2026

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

Ancestral population genomics.

Julien Y Dutheil1, Asger Hobolth

  • 1Institut des Sciences de l'Évolution Montpellier (ISE-M), UMR 5554, CNRS, Unversité Montpellier, Montpellier, France. julien.dutheil@univ-montp2.fr

Methods in Molecular Biology (Clifton, N.J.)
|March 9, 2012
PubMed
Summary
This summary is machine-generated.

Population genomics uses complete genomes from closely related species to infer ancestral population sizes and split times. Analyzing these genomes helps understand speciation, recombination, and selection forces.

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Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
09:37

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

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Last Updated: May 24, 2026

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
09:37

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

Area of Science:

  • Population genetics
  • Phylogenetics
  • Genomics

Background:

  • Availability of complete genomes for closely related species enables new research avenues.
  • Population genetics and phylogenetics are key disciplines for studying speciation.

Purpose of the Study:

  • To model sequence evolution during speciation.
  • To estimate population genetics parameters like ancestral population sizes and split times.
  • To investigate recombination processes and selective forces.

Main Methods:

  • Analyzing genomic data from closely related species.
  • Utilizing speciation models, including isolation and isolation-with-migration models.
  • Decoding mosaic histories within genomes due to recombination.

Main Results:

  • A few complete genomes can provide substantial population information.
  • Recombination creates segments with distinct evolutionary histories within genomes.
  • Population genomics aims to infer demographic and selection scenarios from genomic data.

Conclusions:

  • Population genomics offers powerful tools for understanding species evolution.
  • Careful modeling of sequence evolution is crucial for accurate parameter estimation.
  • Computational and statistical challenges remain in analyzing population genomics data.