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The Micturition Reflex

The Micturition Reflex

Urination, or micturition involves the coordination of the bladder's detrusor muscle and two sphincters to ensure controlled bladder emptying.
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating urine...

Urinary Bladder

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Anatomy of the Genitourinary System II: Bladder and Urethra

Anatomy of the Genitourinary System II: Bladder and Urethra

The lower urinary system consists of the urinary bladder and urethra, which are essential in storing and expelling urine from the body. Together with the internal and external sphincters, these structures work together to regulate urination effectively.Anatomy of the BladderThe urinary bladder is a muscular, stretchable organ behind the pubic bone and in front of the rectum. In females, the bladder is positioned anterior to the vagina and inferior to the uterus, while in males, it is located...

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Related Experiment Video

Updated: May 24, 2026

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Published on: August 28, 2020

Neurogenic bladder.

Peter T Dorsher¹, Peter M McIntosh

¹Department of Physical Medicine and Rehabilitation, Mayo College of Medicine, 4500 San Pablo Road, Jacksonville, FL 32224, USA.

Advances in Urology

|March 9, 2012

Summary

This summary is machine-generated.

Neurogenic bladder dysfunction, caused by neurological conditions, can lead to serious health issues. Comprehensive bladder retraining programs effectively manage symptoms and improve quality of life.

More Related Videos

A Decentralized (Ex Vivo) Murine Bladder Model with the Detrusor Muscle Removed for Direct Access to the Suburothelium during Bladder Filling

A Decentralized (Ex Vivo) Murine Bladder Model with the Detrusor Muscle Removed for Direct Access to the Suburothelium during Bladder Filling

Published on: November 28, 2019

Related Experiment Videos

Last Updated: May 24, 2026

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Published on: August 28, 2020

A Decentralized (Ex Vivo) Murine Bladder Model with the Detrusor Muscle Removed for Direct Access to the Suburothelium during Bladder Filling

A Decentralized (Ex Vivo) Murine Bladder Model with the Detrusor Muscle Removed for Direct Access to the Suburothelium during Bladder Filling

Published on: November 28, 2019

Area of Science:

Urology
Neurology
Nephrology

Background:

Neurogenic bladder dysfunction stems from congenital anomalies (e.g., meningomyelocele) or nervous system damage.
Untreated, it causes renal damage, infections, and incontinence, impacting physical and psychological well-being.

Purpose of the Study:

To outline a comprehensive bladder retraining program for neurogenic bladder dysfunction.
To detail goals including preventing incontinence, UTIs, and upper urinary tract damage.
To explore future pharmacological, surgical, and regenerative medicine interventions.

Main Methods:

Review of physiological and pathophysiological principles of micturition.
Integration of education, training, medication, and surgical interventions.
Discussion of current and future treatment modalities.

Main Results:

Bladder retraining mitigates adverse consequences of neurogenic bladder dysfunction.
Effective management improves quantity and quality of life.
Understanding micturition is key to selecting appropriate treatments.

Conclusions:

Comprehensive bladder retraining is crucial for managing neurogenic bladder dysfunction.
Multifaceted approaches are necessary to prevent complications and enhance patient outcomes.
Ongoing research into novel therapies promises improved future treatments.