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Non-small cell lung carcinoma therapy using mTOR-siRNA

Hirochika Matsubara1, Kenji Sakakibara, Tamo Kunimitsu

  • 1Division of Thoracic and Cardiovascular Surgery, Department of Surgery, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan. hmatsu@yamanashi.ac.jp

International Journal of Clinical and Experimental Pathology
|March 9, 2012
PubMed
Summary

Small interfering RNA (siRNA) targeting the mammalian target of rapamycin (mTOR) effectively inhibits non-small-cell lung cancer (NSCLC) cell proliferation and migration while increasing apoptosis in vitro.

Keywords:
mTORnon-small-cell lung cancersiRNA

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