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Published on: November 20, 2015
Insights
Acute lead poisoning in an infant was diagnosed in Oman using X-rays and high blood lead levels. Early detection and treatment with calcium edetate (EDTA) therapy prevented complications.
Area of Science:
- Toxicology
- Pediatrics
- Environmental Health
Background:
- Acute lead poisoning in infants can occur without obvious neurological symptoms.
- Traditional remedies are a potential source of heavy metal exposure in children.
Observation:
- A case in Oman involved an infant diagnosed with lead poisoning via abdominal X-rays and elevated blood lead levels (83.3 µg/dL).
- The infant received a traditional remedy containing 20.2% inorganic lead for constipation.
- Radio-opaque speckles were visible on the infant's abdominal X-ray.
Findings:
- Treatment with intravenous calcium edetate (EDTA) effectively reduced blood lead levels.
- Prompt diagnosis and intervention mitigated potential encephalopathy and long-term sequelae.
Implications:
- Highlights the importance of considering lead poisoning in infants presenting with non-specific symptoms.
- Underscores the need for parental education on the risks associated with traditional remedies.
- Emphasizes the critical role of toxicology screening in diagnosing environmental exposures.
Abstract:
A case of acute lead poisoning in an infant without overt clinical manifestations of encephalopathy is reported for the first time in Oman. The case was diagnosed at Rustaq Hospital on the basis of (i) history by the mother of giving the child a traditional remedy for treating constipation (ii) X-ray of abdomen showing radio-opaque speckles and (iii) detection of high blood lead levels (83.3 µg/dL) at the toxicology laboratory of the poison control centre. The source of lead was confirmed by high content of inorganic lead (20.2%) found in the sample of the traditional remedy (bint al dahab). The blood lead levels significantly decreased, after the intravenous calcium edetate (EDTA) therapy was given to the baby. The case highlights that early detection and treatment of acute lead poisoning in children can prevent morbidity and sequelae associated with encephalopathy. It also indicated the need for awareness and prevention programme for parents on this issue.
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