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Updated: May 24, 2026

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae
Published on: February 24, 2023
Increased detection of Mycoplasma pneumoniae infection in children, Lyon, France, 2010 to 2011
D Eibach1, J S Casalegno, V Escuret
1Laboratory of Virology, Centre de Biologie et Pathologie Est, Hospices Civils de Lyon, Lyon, France. daniel.eibach@chu-lyon.fr
Insights
Mycoplasma pneumoniae infections increased in children aged 5-15 years in northern Europe and France. Laboratory data confirmed a rise in M. pneumoniae detection via real-time PCR in this age group.
Area of Science:
- Pediatric Infectious Diseases
- Respiratory Pathogens
- Epidemiology
Background:
- Recent reports indicate a rise in Mycoplasma pneumoniae infections across northern Europe.
- This increase is particularly noted in children aged 5–15 years.
- Mycoplasma pneumoniae is a common cause of community-acquired pneumonia.
Purpose of the Study:
- To analyze laboratory data for Mycoplasma pneumoniae detection trends.
- To investigate the prevalence of M. pneumoniae in pediatric patients.
- To identify epidemic peaks of M. pneumoniae infection in France.
Main Methods:
- Analysis of a laboratory database.
- Real-time polymerase chain reaction (PCR) for M. pneumoniae detection.
- Retrospective review of respiratory sample results.
Main Results:
- A higher proportion of respiratory samples tested positive for M. pneumoniae.
- The increase was significant in the pediatric age group of 5–15 years.
- France experienced its first M. pneumoniae epidemic peak since 2005 in 2010–2011.
Conclusions:
- Laboratory data confirm an increasing trend of Mycoplasma pneumoniae infections in children.
- The findings align with reports from other northern European countries.
- France experienced a notable M. pneumoniae epidemic in 2010–2011, primarily affecting school-aged children.
Abstract:
Recent reports from several northern European countries indicate an increase in detection of Mycoplasma pneumoniae infection in the past two years, notably in children aged 5–15 years. Analysis of our laboratory database showed a similar pattern, with a higher proportion of respiratory samples positive for M. pneumonia by real-time PCR in paediatric patients aged 5–15 years. Our data indicate that in 2010 and 2011, France experienced the first epidemic peak of M. pneumonia infection since 2005.
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