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Extrachromosomal microDNAs and chromosomal microdeletions in normal tissues

Yoshiyuki Shibata1, Pankaj Kumar, Ryan Layer

  • 1Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA.

Science (New York, N.Y.)
|March 10, 2012
PubMed
Summary

Scientists discovered novel circular DNA fragments, called microDNAs, in mammalian cells. Their formation may explain certain genetic deletions found in both somatic and germline DNA.

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