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Updated: May 24, 2026

In vivo Measurement of Knee Extensor Muscle Function in Mice
Published on: March 4, 2021
Effects of Russian current and low-frequency pulsed current on discomfort level and current amplitude at 10% maximal
Marco Aurélio Vaz1, Fernando Amâncio Aragão, Émerson S Boschi
1Exercise Research Laboratory, School of Physical Education, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil.
Background:
Low-frequency pulsed current (LFPC) and Russian current (RC), a type of kilohertz-frequency alternating current, have been frequently used for muscle strengthening in rehabilitation programs. Despite the popularity of these current types, it is unclear which is most effectively able to generate a similar submaximal torque with minimal discomfort and current amplitude.
Objective:
To compare discomfort and current amplitude between LFPC and RC to achieve a knee extensor torque of 10% of the maximal isometric voluntary contraction (MIVC).
Methods:
Twenty-two healthy subjects were subjected to three electrically elicited knee extensor submaximal contractions (10% MIVC) that were sustained for 10 seconds. The current amplitude required to achieve 10% MIVC and subjective discomfort were assessed directly by the electrical stimulator and with the Visual Analogue Pain Scale, respectively. A paired t-test was used to determine differences between the electrical currents (α = 0.05).
Results:
LFPC required significantly lower current amplitude (15%) and a lower discomfort level (50%) to achieve 10% of MIVC compared to RC.
Conclusion:
LFPC current seems to be more effective than RC with respect to discomfort level and current amplitude to produce 10% of MIVC.

