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Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase
Published on: April 29, 2010
Keeping it together in times of stress: checkpoint function at stalled replication forks
Theresa J Berens1, David P Toczyski
1Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA.
Molecular Cell
|March 13, 2012
Abstract:
In this issue of Molecular Cell, De Piccoli et al. (2012) show that, contrary to current models of DNA replication checkpoint function, replication proteins remain associated with each other and with replicating DNA when replication is stressed in checkpoint-deficient cells.
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