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Updated: May 24, 2026
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Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
Rare thoracic cancers, including peritoneum mesothelioma
Sabine Siesling1, Jan Maarten van der Zwan, Isabel Izarzugaza
1Department of Registry and Research, Comprehensive Cancer Centre The Netherlands, PO Box 330, 9700 AH Groningen, The Netherlands. s.siesling@iknl.nl
European Journal of Cancer (Oxford, England : 1990)
|March 13, 2012
Summary
This study analyzed rare thoracic cancers, finding mesothelioma most common and prevalent. Thymus tumors had the best survival rates, while mesothelioma had the lowest.
Area of Science:
- Oncology
- Epidemiology
- Public Health
Background:
- Rare thoracic cancers, including thymus, trachea, and mesothelioma, pose a significant health burden.
- Understanding their incidence, prevalence, and survival is crucial for effective management and policy-making.
Purpose of the Study:
- To describe the incidence, prevalence, and survival of rare thoracic tumors.
- To utilize a large database encompassing cancer patients diagnosed between 1978 and 2002.
Main Methods:
- Analysis of over 17,688 rare thoracic cancer cases from 89 population-based cancer registries.
- Data followed up to December 31, 2003, using the RACECARE project criteria.
Main Results:
- Mesothelioma was the most common rare thoracic tumor (19/million/year), followed by thymus (1.7/million/year) and trachea (1.3/million/year).
- Incidence rates varied geographically, with higher rates for tracheal tumors in Eastern/Southern Europe and mesothelioma in UK/Ireland.
- Tumors of the thymus showed the best prognosis (5-year survival 66%), while mesothelioma had the poorest (5-year survival 5%).
Conclusions:
- Cancer registry data are vital for assessing the burden of rare thoracic cancers.
- Monitoring these cancers can inform policies related to asbestos exposure and smoking cessation.
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