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Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline
Published on: December 7, 2021
From plant gene regulatory grids to network dynamics.
Maria Katherine Mejia-Guerra1, Marcelo Pomeranz, Kengo Morohashi
1The Ohio State University, Columbus, OH 43210, USA.
Biochimica Et Biophysica Acta
|March 13, 2012
Summary
Gene regulatory networks (GRNs) control how DNA becomes observable traits. This review covers advancements in mapping plant GRNs, tools used, and emerging network dynamics research.
Area of Science:
- Molecular Biology
- Systems Biology
- Genetics
Background:
- Gene expression regulation is fundamental to genotype-phenotype manifestation.
- Gene regulatory networks (GRNs) orchestrate spatial and temporal gene expression via transcription factors and microRNAs in eukaryotes.
- GRN studies in yeast, E. coli, and animals have revealed principles of complex regulatory behaviors.
Purpose of the Study:
- To review recent advancements in the study of plant gene regulatory networks.
- To describe the tools and techniques employed for GRN mapping in plants.
- To discuss the emerging field of network dynamics and its measurement in plants.
Main Methods:
- Review of existing literature on plant GRN research.
- Description of tools and techniques for GRN mapping.
- Discussion of methodologies for measuring network dynamics.
Main Results:
- Plant GRN research is rapidly advancing due to high-quality genomes and new mapping tools.
- Various tools and techniques are available for constructing plant GRNs.
- Methods for measuring plant network dynamics are under development.
Conclusions:
- The study of plant GRNs is a burgeoning field with significant potential.
- Understanding plant GRN dynamics is crucial for comprehending plant development and responses.
- Continued development of tools and methods will accelerate discoveries in plant systems biology.
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