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Related Concept Videos

Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...

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Related Experiment Video

Updated: May 24, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
04:38

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

Published on: May 22, 2019

Pain following stroke: a prospective study.

A P Hansen1, N S Marcussen, H Klit

  • 1Danish Pain Research Center, Aarhus University Hospital, Denmark. anne.hansen@ki.au.dk

European Journal of Pain (London, England)
|March 13, 2012
PubMed
Summary
This summary is machine-generated.

Nearly half of stroke survivors experience new pain within six months, impacting their quality of life. This study quantifies various post-stroke pain types, including headache and central post-stroke pain.

Related Experiment Videos

Last Updated: May 24, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
04:38

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

Published on: May 22, 2019

Area of Science:

  • Neurology
  • Pain Medicine
  • Rehabilitation

Background:

  • Post-stroke pain significantly impacts stroke survivors' quality of life.
  • The precise incidence and severity of various pain types, including central post-stroke pain, remain incompletely understood.

Purpose of the Study:

  • To prospectively determine the incidence and intensity of newly developed pain after stroke.
  • To investigate specific pain types: headache, shoulder pain, other joint pain, and central post-stroke pain.

Main Methods:

  • A prospective study involving 299 consecutive stroke patients admitted to a neurology department.
  • Structured interviews and sensory examinations were conducted within 4 days of admission.
  • Follow-up via phone at 3 and 6 months post-stroke, with 275 patients completing the study.

Main Results:

  • At 6 months, 45.8% of patients reported newly developed pain.
  • Specific pain types included headache (13.1%), shoulder pain (16.4%), other joint pain (11.7%), and evoked pain (8.0%).
  • 10.5% were classified with possible central post-stroke pain, and 33.6% experienced moderate to severe impact on daily life.

Conclusions:

  • Post-stroke pain is highly prevalent, with nearly half of patients developing new pain 6 months after stroke.
  • A significant proportion of patients experience multiple pain types and functional limitations.