Related Experiment Videos
[Precautions before starting a treatment for osteoporosis]
1Service de rhumatologie, CHU de Nice, hôpital L'Archet 1,06200 Nice. breuil.v@chu-nice.fr
Abstract:
To be optimal, the treatment of osteoporosis must be global, including nonpharmacological measures. At the initiation of the treatment, a personalized evaluation of the patient must be realized on diet, physical activity, risk of fall and adhesion of the patient. Dietary calcium is estimated and advices given to attain 1000 in 1200 mg/day and limit excessive coffee, soft drinks and salt intake. Dietary calcium is recommended, but if it is impossible, a complement is prescribed, adapted to the intensity of the deficiency. Serum 25-(OH)-vitamine D is measured and, if below 30 ng/ml, a supplementation prescribed. Low protein intake is looked for and corrected if necessary. Advises are given to limit the alcohol to 2 units/day, stop smoking and to have a regular and high impact physical activity. Subjects at risk of fall must be identified and risk factors corrected if possible. Dental recommandations for the use of bisphosphonates in osteoporosis must be apply. Finally, patient education could be used to optimize patient adherence to pharmacological and non pharmacological anti-osteoporotic treatments.
Related Concept Videos
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Essential Minerals for Bone Health
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Osteoclasts in Bone Remodeling
Urinary Tract Calculi IV: Nutrition Therapy and Prevention
Hormones and Bone Tissue
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...