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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
[Clinical and social problems in controlling multidrug-resistant organisms]
1Department of Infection Control Science, Juntendo University, Graduate School of Medicine.
Nihon Rinsho. Japanese Journal of Clinical Medicine
|March 15, 2012
Summary
Controlling multidrug-resistant Gram-negative bacilli, including Pseudomonas aeruginosa and Acinetobacter baumannii, is challenging. This statement offers guidance for Japanese healthcare facilities to combat these resistant infections.
Area of Science:
- Infectious Diseases
- Microbiology
- Public Health
Context:
- Emergence of multidrug-resistant Gram-negative bacilli (MDRP and MDR-Ab) presents significant healthcare challenges.
- Existing guidelines from CDC (2006) and APIC (2010) provide a foundation for infection control.
- The Japanese Society of Environmental Infections (JSEI) responded to a major MDR-Ab outbreak with a position statement.
Purpose:
- To provide clear directions for controlling multidrug-resistant Gram-negative bacilli in Japanese healthcare settings.
- To assist facilities in developing comprehensive infection control strategies.
- To address critical points and necessary discussions for effective management.
Summary:
- This report assesses critical points for controlling multidrug-resistant Gram-negative bacilli.
- It aims to guide Japanese healthcare facilities in infection control planning.
- The statement addresses the need for evidence-based strategies against emerging resistant pathogens.
Impact:
- Enhances infection control practices in Japanese healthcare facilities.
- Contributes to managing the spread of multidrug-resistant organisms.
- Supports the development of targeted strategies against resistant Gram-negative bacilli.
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