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Updated: May 24, 2026
Gold Nanoparticle Synthesis
Published on: July 10, 2021
Gold nanoparticle-induced formation of artificial protein capsids
Ali D Malay1, Jonathan G Heddle, Satoshi Tomita
1Graduate School of Materials Science, Nara Institute of Science and Technology (NAIST), and CREST, Japan Science and Technology Agency, 8916-5 Takayama, Ikoma, Nara 630-0192, Japan.
Abstract:
Gold nanoparticles are generally considered to be biologically inactive. However, in this study we show that the addition of 1.4 nm diameter gold nanoparticle induces the remodeling of the ring-shaped protein TRAP into a hollow, capsid-like configuration. This structural remodeling is dependent upon the presence of cysteine residues on the TRAP surface as well as the specific type of gold nanoparticle. The results reveal an apparent novel catalytic role of gold nanoparticles.
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