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Updated: May 24, 2026

Image-Based Methods to Study Membrane Trafficking Events in Stomatal Lineage Cells
Published on: May 12, 2023
Mechanisms for calcium sensing receptor-regulated stomatal closure in response to the extracellular calcium signal
1Key Laboratory for Subtropical Wetland Ecosystem Research of MOE, College of the Environment and Ecology, Xiamen University, Xiamen, China.
Abstract:
In Arabidopsis, extracellular calcium (Ca²⁺(o)) promotes intracellular calcium (Ca²⁺(i)) transients and stomatal closure, which has been found to be regulated by the calcium sensing receptor (CAS). However, the detailed pathways for transducting the Ca²⁺(o) signal by CAS are still unclear. We found that nitric oxide (NO) and the hydrogen peroxide (H₂O₂) accumulated in the guard cell chloroplast were the two elements that act downstream of the CAS signaling and trigger the stomatal closure by prolonging Ca²⁺(i) transients. Here we provide more commentary on CAS-regulated H₂O₂ generation from chloroplast and Ca²⁺(i) transients in response to Ca²⁺(o), as well as other potential mechanisms that may be involved in the CAS signaling pathway.
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