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Related Experiment Videos

Extrahepatic biliary obstruction by lymphoma.

E Feller1, F J Schiffman

  • 1Department of Medicine, Miriam Hospital/Brown University, Providence, RI 02906.

Archives of Surgery (Chicago, Ill. : 1960)
|November 1, 1990
PubMed
Summary
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Enlarged lymph nodes from lymphoma can rarely cause obstructive jaundice. Endoscopic retrograde cholangiopancreatography aids diagnosis, and treatment with bypass and chemotherapy offers rapid symptom relief.

Area of Science:

  • Gastroenterology and Oncology
  • Hepatobiliary Medicine

Background:

  • Obstructive jaundice is typically caused by gallstones or tumors.
  • Lymphoma can uncommonly present with extrinsic compression of the common bile duct.

Observation:

  • Two patients with lymphoma developed obstructive jaundice due to enlarged lymph nodes.
  • Endoscopic retrograde cholangiopancreatography (ERCP) was utilized to diagnose the condition.

Findings:

  • ERCP effectively differentiated lymphomatous biliary obstruction from other causes of jaundice in lymphoma patients.
  • Nonoperative biliary bypass combined with chemotherapy and/or radiotherapy led to rapid symptom and biochemical resolution.

Implications:

  • Lymphomatous biliary obstruction is a treatable cause of jaundice in lymphoma patients.

Related Experiment Videos

  • ERCP is a valuable diagnostic and therapeutic tool for this rare complication.
  • Early consideration of lymphoma is crucial for timely management of obstructive jaundice.