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Updated: May 24, 2026

09:34
Structured Motor Rehabilitation After Selective Nerve Transfers
Published on: August 15, 2019
Recovery of motor function after stroke.
Nikhil Sharma1, Leonardo G Cohen
1Human Cortical Physiology and Stroke Neurorehabilitation Section, NINDS, NIH, Bethesda, Maryland, USA. sharmanik@ninds.nih.gov
Developmental Psychobiology
|March 15, 2012
Summary
Neuroplasticity enables brain adaptation throughout life, crucial for recovery from stroke. New research highlights non-primary motor cortex interactions and neuromodulation techniques like TMS and tDCS for motor rehabilitation.
Area of Science:
- Neuroscience
- Neurology
- Rehabilitation Medicine
Background:
- The human brain exhibits neuroplasticity, adapting to anatomical and environmental changes.
- Neuroplasticity is vital throughout life, especially in neurological conditions like amblyopia and stroke.
- Understanding mechanisms of functional deficits post-stroke is crucial for effective treatment.
Purpose of the Study:
- To review new insights into mechanisms of functional deficits after adult-onset stroke.
- To explore functional interactions between brain regions contributing to motor disability.
- To identify potential interventional approaches for motor stroke rehabilitation.
Main Methods:
- Literature review focusing on neuroplasticity and stroke mechanisms.
- Analysis of functional interactions between primary and non-primary motor areas.
- Examination of emerging neuromodulation techniques for neurorehabilitation.
Main Results:
- New understanding points to the involvement of non-primary motor areas in stroke-related motor deficits.
- Interactions between non-primary and primary motor cortices are identified as key areas of interest.
- Evidence suggests potential for neuromodulation therapies in stroke recovery.
Conclusions:
- Understanding brain region interactions is key to addressing motor deficits after stroke.
- Neuromodulation techniques like transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) show promise for neurorehabilitation.
- These findings may inform interventions for stroke and other neurological disorders like amblyopia.

