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Glued carbon fiber electrodes for diaphragm pacing
1Graduate School of Electronic Science and Technology, Shizuoka University, Hamamatsu, Japan.
Artificial Organs
|October 1, 1990
Summary
New carbon fiber electrodes with fibrin glue enable effective diaphragm pacing in dogs for 9 weeks. This minimally invasive method preserves nerve integrity and reduces surgical risks.
Area of Science:
- Biomedical Engineering
- Neurosurgery
- Respiratory Physiology
Background:
- Diaphragm pacing is crucial for respiratory support in certain conditions.
- Current electrode implantation methods can be invasive, risking nerve damage.
Purpose of the Study:
- To evaluate the efficacy and safety of novel carbon fiber electrodes for diaphragm pacing.
- To assess the long-term performance of fibrin glue-secured electrodes.
Main Methods:
- Carbon fiber electrodes were applied to the phrenic nerves of three mongrel dogs using fibrinogen and thrombin.
- Tidal volumes and threshold current were measured up to 9 weeks post-implantation.
Main Results:
- Effective diaphragm contractions were observed for the entire 9-week study period.
- The fibrin glue method ensured stable electrode placement without nerve exfoliation.
Conclusions:
- Carbon fiber electrodes secured with fibrin glue offer a safe and effective method for diaphragm pacing.
- This technique minimizes surgical invasiveness and preserves phrenic nerve function.