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A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis
Published on: September 10, 2014
Electrical tracing-assisted dual-microring label‑free optical bio/chemical sensors
Junfeng Song1, Xianshu Luo, Xiaoguang Tu
1Institute of Microelectronics, A*STAR (Agency for Science, Technology and Research), 11 Science Park Road, Science Park II, Singapore 117685, Singapore. songjf@ime.a-star.edu.sg
Abstract:
We propose and demonstrate a novel electrical tracing-assisted dual-microring resonator-based optical sensor system in silicon-on-insulator substrate. The system comprises one microring resonator-based sensing element and another microring resonator-based tracing element integrated with electrical controller. The resonance wavelength shift of sensing microring induced by the refractive index change is traced and determined by direct voltage supply of the electrical tunable tracing microring. Such optical sensing system eliminates the traditional wavelength-scanning method thus provide a cost effective sensing scheme. Proof-of-principle demonstration by testing polyelectrolyte multilayer shows the sensitivity of ~4.0 mW/ng∙mm-2 and the detection limit of ~5.35 pg/mm2.
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