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Updated: May 24, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Implementation of a clinical decision support system for antimicrobial stewardship
Elizabeth D Hermsen1, Trevor C VanSchooneveld, Harlan Sayles
1Pharmacy Relations and Clinical Decision Support, Nebraska Medical Center, Omaha, Nebraska, USA. elizabeth.hermsen@cubist.com
Abstract:
Clinical decision support systems (CDSSs) for antimicrobial stewardship require considerable human resources and financial investments. This pre-/postimplementation study evaluated the effect of a CDSS on performance of prospective audit with intervention and feedback and demonstrated an increase in interventions and recommendation acceptance countered by a substantial number of nonactionable alerts.
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