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Concise review: Immune recognition of induced pluripotent stem cells

Ashleigh S Boyd1, Neil P Rodrigues, Kathy O Lui

  • 1NIH Center of Biomedical Research Excellence in Stem Cell Biology, Roger Williams Medical Center, Boston University School of Medicine, Providence, Rhode Island 02908, USA. asboyd@bu.edu

Stem Cells (Dayton, Ohio)
|March 16, 2012
PubMed

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Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...
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