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Photodynamic therapy for basal cell carcinomas in organ-transplant recipients
1Department of Dermatology, Oslo University Hospital Rikshospitalet, Oslo, Norway. gguleng@hotmail.com
Abstract:
The incidence of nonmelanoma skin cancer is significantly increased in recipients of solid-organ transplants. Photodynamic therapy (PDT) is a well-documented treatment option for superficial and selected nodular basal cell carcinomas (BCCs) in immunocompetent patients, but there are few reports describing PDT of BCCs in organ-transplant recipients (OTRs). We report a study of 18 OTRs with BCC on the head and trunk, who were treated with PDT, using methyl aminolevulinate as photosensitizer. There was only one recurrence during a total follow-up period of 407 months. PDT seems to be an effective treatment option for BCC in immunosuppressed OTRs.
