Related Experiment Video
Updated: May 24, 2026
Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
Published on: March 31, 2021
Antibacterial activity of a new mineral trioxide aggregate-based root canal sealer
Zahed Mohammadi1, Luciano Giardino, Flavio Palazzi
1Department of Endodontics, Hamedan University of Medical Sciences, Iran. zahed_mohammadi@yahoo.com
Objectives:
To compare the antibacterial effect of AH-26, white-coloured mineral trioxide aggregate (WMTA) and CPM sealer against Staphylococcus aureus and Streptococcus mutans after 24 h and 1 week.
Materials And Methods:
All materials were prepared according to the manufacturers' directions immediately before testing. The antibacterial effect of each agent was determined by measuring the diameter of the zone of inhibition in millimetres after incubation at 37°C for 24 h and 7 days in a humid atmosphere. Each test was repeated three times.
Results:
In the 24-h and 7-day samples, the antibacterial activity of AH-26 was significantly greater than that of the two other materials tested against both bacteria (P < 0.05). The antibacterial activities of CPM sealer and WMTA against S. aureus were not significantly different (P > 0.05) in 24-h or 7-day samples, but CPM sealer demonstrated a significantly greater effect than WMTA against S. mutans (P < 0.05).
Conclusion:
All products studied exhibited antibacterial activity. However, in 24-h and 7-day samples, AH-26 exerted the greatest activity against both organisms tested.