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Updated: May 24, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
[Treatment of clozapine-induced tachycardia with propranolol complicated by psoriasis]
D van Dam1, T M Bosch, E J Mookhoek
1Delta psychiatrisch centrum, Postbus 800, 3170 DZ Poortugaal. d.van.dam@deltapsy.nl
Abstract:
A 25-year-old male developed sinus tachycardia after given clozapine for treatment-resistant psychosis in schizophrenia. The tachycardia was treated successfully with propranolol for several weeks. The patient developed skin eruptions, later diagnosed as psoriasis. Propranolol is known to be capable of causing, evoking or aggravating psoriasis. Several other drugs commonly used in psychiatric practice are also known to cause psoriasis. Doctors need to be aware to the possible side effects of such drugs because they can jeopardise the patient's wellbeing and reduce the efficacy of psychiatric treatment.
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