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Published on: February 2, 2024
Chemical constituents of Euphorbia tangutica
Ben-Yin Zhang1, Huan Wang, Xiao-Dong Luo
1Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810008, China.
Abstract:
Sixteen known compounds isolated from the whole plants of Euphorbia tangutica, including phorbol-13-actate (1) previously synthesised and obtained from a natural source for the first time, were evaluated in vitro against a panel of human cancer cell lines using the MTT method. Among them, ergosterol (6) exhibited significant cytotoxic activity against HL-60 cell line with an IC(50) value of 3.3 µM, and 3β,5α-dihydroxy-15β-cinnamoyloxy-14-oxolathyra-6 Z,12 E-diene (7) also displayed moderate activity.
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