[Epigenetics and colorectal cancer]
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Updated: May 24, 2026

In vitro Organoid Culture of Primary Mouse Colon Tumors
Published on: May 17, 2013
Pablo Menéndez1, Pedro Villarejo, David Padilla
1Servicio de Cirugía General y de Aparato Digestivo, Hospital Gutiérrez Ortega, Valdepeñas, Ciudad Real, España. pablomensan@hotmail.com
Abstract:
The epigenetic and physiological mechanisms that alter the structure of chromatin include the methylation of DNA, changes in the histones, and changes in RNA. A literature review has been carried out using PubMed on the evidence published on the association between epigenetics and colorectal cancer. The scientific literature shows that epigenetic changes, such as genetic modifications may be very significant in the origin of neoplastic disease, contributing both to the development and progression of the disease.
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