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Novel live alkaline phosphatase substrate for identification of pluripotent stem cells

Upinder Singh1, Rene H Quintanilla, Scott Grecian

  • 1Molecular Probes, Life Technologies, 29851 Willow Creek Road, Eugene, OR 97402, USA.

Stem Cell Reviews and Reports
|March 20, 2012
PubMed
Abstract

No abstract available in PubMed .

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Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...