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Spartium junceum aromatic water: chemical composition and antitumor activity
Teresa Cerchiara1, Serafina V Straface, Giuseppe Chidichimo
1Department of Pharmaceutical Sciences, Via San Donato 19/2, Bologna University, 40127 Bologna, Italy. teresa.cerchiara2@unibo.it
Abstract:
The purpose of this study was to analyse the chemical composition of Spartium junceum L. (also known as Spanish Broom) aromatic water and to evaluate its cytotoxic activity against a series of human cancer cell lines (melanoma: RPMI 7932; leukemia: K562; breast cancer cell: MCF7-Bart and MCF7-ICLC, colon adenocarcinoma: SW480). The results show that the aromatic water was cytotoxic toward the tumor cell lines analyzed (RPMI 7932, K562, MCF7-Bart, MCF7-ICLC, SW480), while it did not appreciably alter the viability of normal keratinocytes (NCTC 2544) suggesting its potential use as an antitumor agent for cancer treatment and/or prevention.
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