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Related Concept Videos

Diabetes Mellitus: Introduction01:26

Diabetes Mellitus: Introduction

Diabetes mellitus consists of chronic metabolic disorders characterized by persistent hyperglycemia. This elevated blood glucose results from defects in insulin secretion, impaired insulin action, or both. Insulin, produced by pancreatic β-cells, is essential for maintaining glucose homeostasis by facilitating cellular glucose uptake for energy or storage. Disruptions in insulin production or function lead to glucose accumulation in the bloodstream, causing the clinical features and long-term...
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type I Diabetes III: Clinical Manifestations01:19

Type I Diabetes III: Clinical Manifestations

Type 1 diabetes mellitus typically presents with rapid-onset symptoms due to the body’s inability to utilize glucose in the absence of insulin. Since insulin is required for glucose uptake into cells, its deficiency leads to hyperglycemia and cellular energy deprivation, resulting in characteristic clinical features.Polyuria and PolydipsiaOne of the earliest, most prominent symptoms is polyuria (excessive urination). When blood glucose concentrations rise above the renal threshold, the kidneys...
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Type II Diabetes II: Pathophysiology01:24

Type II Diabetes II: Pathophysiology

PathophysiologyType 2 diabetes mellitus (T2DM ) is a chronic metabolic disorder characterized by insulin resistance and progressive pancreatic β-cell dysfunction, leading to impaired glucose homeostasis. It results from interactions among genetic predisposition, environmental factors, and metabolic stressors, such as overnutrition and a sedentary lifestyle.Insulin Resistance and Glucose DysregulationEarly T2DM involves insulin resistance in skeletal muscle, adipose tissue, and the liver.

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Extracellular Glucose Depletion as an Indirect Measure of Glucose Uptake in Cells and Tissues Ex Vivo
10:35

Extracellular Glucose Depletion as an Indirect Measure of Glucose Uptake in Cells and Tissues Ex Vivo

Published on: April 6, 2022

[Diabetes mellitus].

M Ahdi1, V E A Gerdes, J B L Hoekstra

  • 1Uit de afdeling Interne Geneeskunde van het Slotervaartziekenhuis in Amsterdam, 2de afdeling Vasculaire Geneeskunde en 3de afdeling Inwendige geneeskunde van het Academisch Medisch Centrum/Universiteit van Amsterdam. mohamed.ahdi@slz.nl

Nederlands Tijdschrift Voor Tandheelkunde
|March 21, 2012
PubMed
Summary
This summary is machine-generated.

Diabetes mellitus, particularly type 2, affects over 740,000 in the Netherlands, increasing risks of complications like gum disease. Effective diabetes care requires collaboration among healthcare professionals to manage the condition and prevent severe outcomes.

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Area of Science:

  • Endocrinology and Metabolism
  • Oral Health and Periodontology
  • Public Health and Epidemiology

Context:

  • Diabetes mellitus prevalence is rising in the Netherlands, with over 740,000 individuals affected.
  • Type 2 diabetes, accounting for 90% of cases, is frequently linked to obesity, hypertension, and high cholesterol.
  • Diabetes complications, including gingivitis and periodontitis, pose significant long-term health risks.

Purpose:

  • To highlight the increasing prevalence of diabetes mellitus in the Netherlands.
  • To underscore the association between diabetes mellitus and oral health issues like periodontitis.
  • To emphasize the critical need for interprofessional collaboration in managing diabetes care.

Summary:

  • The Netherlands faces a growing diabetes mellitus epidemic, predominantly type 2, impacting over 740,000 people.
  • Diabetes is strongly correlated with metabolic conditions and increases the risk of severe, irreversible organ damage.
  • Oral health conditions, such as gingivitis and periodontitis, are recognized as diabetes complications.

Impact:

  • Effective management of diabetes mellitus is crucial for preventing long-term complications and irreversible organ damage.
  • Increased incidence of periodontitis in diabetic patients necessitates integrated oral health strategies.
  • Enhanced collaboration among healthcare providers is vital for optimizing patient outcomes and comprehensive diabetes management.