Related Experiment Video
Updated: May 24, 2026

Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis
Published on: July 4, 2007
[Myelitis following vaccination against tick-borne encephalitis]
Pieta Ipatti1, Tapani Tikkakoski, Seppo Tuisku
1Pohjois-Pohjanmaan Sairaanhoitopiiri, Kuvantamisen Vastuualue.
Tick-borne encephalitis (TBE) is a serious disease. This report details the first case of severe myelitis in Finland after receiving the TBE vaccine, highlighting a rare adverse event.
Area of Science:
- Neurology
- Vaccinology
- Infectious Diseases
Background:
- Tick-borne encephalitis (TBE) is a significant neuroinfectious disease prevalent in endemic areas.
- Currently, no specific antiviral treatment exists for TBE.
- Available TBE vaccines are generally considered safe and effective, with severe adverse events being rare.
Observation:
- This study reports the first documented case of severe myelitis in Finland.
- The myelitis occurred following vaccination against tick-borne encephalitis.
Findings:
- The case highlights a rare but severe neurological adverse effect potentially associated with TBE vaccination.
- This observation is crucial for understanding the full spectrum of vaccine safety profiles.
Implications:
- Further investigation into the causal link between TBE vaccination and myelitis is warranted.
- This finding may inform vaccination guidelines and post-vaccination surveillance protocols.
- Enhanced awareness among healthcare providers regarding rare vaccine-related neurological complications is essential.
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