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Published on: June 29, 2013
[Advances in the prevention, diagnosis and therapy of vascular diseases]
Katalin Judit Szabó1, Róza Adány, József Balla
1Debreceni Egyetem, Orvos- és Egészségtudományi Centrum Neurológiai Klinika Debrecen Nagyerdei krt 98. 4032.
Insights
Atherosclerosis is a systemic vascular disease impacting multiple arteries. A holistic approach to diagnosis and therapy is crucial for managing patients with multiorgan involvement.
Area of Science:
- Cardiovascular Medicine
- Vascular Biology
- Public Health
Context:
- Atherosclerosis is a widespread arterial disease with early onset.
- Current clinical practice fragments the diagnosis and treatment of various vascular diseases.
- This fragmentation can lead to polypragmasia and suboptimal patient outcomes.
Purpose:
- To review multidisciplinary advances in understanding and managing atherosclerosis.
- To highlight the limitations of current fragmented medical subfields in addressing systemic vascular disease.
- To advocate for a holistic approach in the diagnosis and therapy of atherosclerosis.
Summary:
- Atherosclerosis affects coronary, carotid, and peripheral arteries, with impairments detectable early in life.
- Common vascular risk factors (hypertension, diabetes, dyslipidemia) contribute to disease progression.
- A holistic approach, as suggested by registries like REACH, is beneficial for patients with multiorgan vascular disease.
Impact:
- Promotes a unified understanding of atherosclerosis as a systemic condition.
- Encourages integrated diagnostic and therapeutic strategies across medical specialties.
- Aims to improve patient outcomes by addressing the multifaceted nature of vascular disease.
Abstract:
Atherosclerosis is a systemic disease affecting the coronary, carotid, intracerebral, renal and peripherial arteries. The early morphological and functional impairments could be detected in the second or third decades of life and their progression depend on the number and severity of risk factors and individual susceptility. Although the vascular risk factors (smoking, overweight, age, unhealthy diet, lack of physical exercise, hypertension, diabetes mellitus, chronic kidney disease and dyslipidemia) are the same and common in the different vascular diseases, the present clinical routine artificially classifies the diagnosis and therapy of different vascular diseases into different subfields of medicine with the negative impact of possible polypragmasia. Recently, worldwide health surveys (e.g. REACH registry) have proven the usefulness of a holistic approach in the diagnosis and therapy of multiorgan-affected vascular patients. This review summarizes the multidisciplinary advances and future perspective of vascular diseases.
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