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Enhancing the Development and Growth of Infant Cerebral Palsy Rats Using Selective Spinal Manipulations
Published on: February 2, 2024
Cerebral palsy among Asian ethnic subgroups
Tess C Lang1, Elena Fuentes-Afflick, William M Gilbert
1Department of Neurology, University of California--San Francisco, San Francisco, CA 94143-0137, USA.
Pediatrics
|March 21, 2012
Summary
Most Asian subgroups have a lower risk of cerebral palsy (CP) than whites. This disparity in CP prevalence remains unexplained by sociodemographic factors, suggesting further research into its causes.
Area of Science:
- Neurology
- Public Health
- Epidemiology
Background:
- Cerebral palsy (CP) prevalence varies across racial and ethnic groups.
- Previous studies indicate a generally reduced risk of CP in Asian populations compared to white populations.
Purpose of the Study:
- To investigate CP risk among specific Asian subgroups compared to whites.
- To determine if sociodemographic factors explain observed disparities in CP prevalence.
Main Methods:
- A retrospective cohort study analyzed over 2.7 million births in California (1991-2001).
- Children diagnosed with CP were identified through the California Department of Health Services.
- Asian subgroups included East Asian, Filipino, Indian, Pacific Islander, Samoan, and Southeast Asian.
Main Results:
- Overall CP prevalence was lower in Asians (1.09/1000) than whites (1.36/1000).
- CP rates varied significantly among Asian subgroups, from 0.61/1000 (Thai) to 2.08/1000 (Samoan).
- After adjusting for maternal age, education, infant gender, and birth weight, East Asians, Filipinos, Indians, Pacific Islanders, and Southeast Asians still showed a lower adjusted risk of CP compared to whites.
Conclusions:
- Most Asian national origin subgroups exhibit a lower CP rate than whites.
- The observed ethnic disparity in CP risk is not explained by the studied sociodemographic factors.
- Further research is needed to understand the underlying causes of ethnic disparities in CP for improved pathogenesis and prevention insights.
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