Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
Aging01:26

Aging

Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multimodal Psychophysiological Assessment of Craving in Patients With Alcohol Dependence During Virtual Reality Cue Exposure: Exploratory Single-Arm Clinical Study.

JMIR serious games·2026
Same author

Failure to detect entorhinal grid-like signals in a passive navigation human fMRI study.

Imaging neuroscience (Cambridge, Mass.)·2026
Same author

General cognitive function and the brain's structural connectome.

bioRxiv : the preprint server for biology·2026
Same author

rTCT: Rodent Triangle Completion Task to Facilitate Reverse Translational Study of Path Integration.

Hippocampus·2026
Same author

Hallmarks of healthy cognitive aging: Inter-individual differences in aging trajectories.

Ageing research reviews·2026
Same author

Equipped for success: genomes and metabolomes of the European Amanita muscaria are conserved in its novel South African range.

The New phytologist·2026
Same journal

Opioid-Associated Hippocampal Injury: Past, Present, and Future Directions.

Hippocampus·2026
Same journal

Neural and Navigational Features Influencing the Novelty Induced Benefits on Episodic Memory.

Hippocampus·2026
Same journal

Intrinsic Persistent Firing in CA1 Encodes Elapsed Time Across Behaviorally Relevant Scales.

Hippocampus·2026
Same journal

Boundary Vector Cells Encode a Future-Biased Spectrum of Positions in the Rat.

Hippocampus·2026
Same journal

Hippocampal NOP Receptor Activation Impairs Object Recognition Memory Acquisition.

Hippocampus·2026
Same journal

Effects of Corticotropin-Releasing Factor 1 Receptor Antagonism on In Vivo Dentate Gyrus Long-Term Potentiation in the TgF344-AD Rat Model of Alzheimer's Disease.

Hippocampus·2026
See all related articles

Related Experiment Video

Updated: May 23, 2026

Assessing Human Spatial Navigation in a Virtual Space and its Sensitivity to Exercise
06:17

Assessing Human Spatial Navigation in a Virtual Space and its Sensitivity to Exercise

Published on: January 26, 2024

Ageing effects on path integration and landmark navigation.

Mathew A Harris1, Thomas Wolbers

  • 1Centre for Cognitive and Neural Systems, University of Edinburgh, Edinburgh, United Kingdom. m.a.harris-2@sms.ed.ac.uk

Hippocampus
|March 21, 2012
PubMed
Summary
This summary is machine-generated.

Older adults show deficits in visual path integration, a key navigation skill. This decline, even with landmarks, suggests a "leaky integrator" mechanism contributing to navigation challenges in aging.

More Related Videos

Modeling the Functional Network for Spatial Navigation in the Human Brain
05:55

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

A Video Demonstration of Preserved Piloting by Scent Tracking but Impaired Dead Reckoning After Fimbria-Fornix Lesions in the Rat
08:37

A Video Demonstration of Preserved Piloting by Scent Tracking but Impaired Dead Reckoning After Fimbria-Fornix Lesions in the Rat

Published on: April 24, 2009

Related Experiment Videos

Last Updated: May 23, 2026

Assessing Human Spatial Navigation in a Virtual Space and its Sensitivity to Exercise
06:17

Assessing Human Spatial Navigation in a Virtual Space and its Sensitivity to Exercise

Published on: January 26, 2024

Modeling the Functional Network for Spatial Navigation in the Human Brain
05:55

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

A Video Demonstration of Preserved Piloting by Scent Tracking but Impaired Dead Reckoning After Fimbria-Fornix Lesions in the Rat
08:37

A Video Demonstration of Preserved Piloting by Scent Tracking but Impaired Dead Reckoning After Fimbria-Fornix Lesions in the Rat

Published on: April 24, 2009

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Gerontology

Background:

  • Navigation abilities decline with normal aging and dementia.
  • Path integration, crucial for navigation, relies on brain regions like the hippocampus and entorhinal cortex, which degenerate with age.
  • Research on age-related deficits in visual path integration and landmark navigation is limited.

Purpose of the Study:

  • To investigate age differences in path integration using virtual navigation tasks.
  • To explore how visual cues (optic flow) and landmark information affect age-related navigation performance.
  • To elucidate the mechanisms underlying age-related navigation decline.

Main Methods:

  • Utilized simple virtual navigation tasks in an environment with optic flow information.
  • Assessed path integration abilities through distance reproduction, rotation reproduction, and triangle completion.
  • Included tasks with and without landmark information to evaluate different navigation strategies.

Main Results:

  • Older participants demonstrated deficits in path integration accuracy (distance, rotation, triangle completion) using only optic flow.
  • Age differences were also observed in triangle completion tasks involving landmark information.
  • Older adults exhibited a more restricted response range, indicative of a 'leaky integrator' model with greater signal decay.

Conclusions:

  • Visual path integration abilities decline with age, impacting navigation.
  • Both optic flow and landmark-based navigation show age-related differences.
  • Findings support a 'leaky integrator' model to explain age-related navigation impairments, contributing to understanding navigation decline in aging.