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Related Experiment Video

Updated: May 23, 2026

Improved Registration of 3D CT Angiography with X-ray Fluoroscopy for Image Fusion During Transcatheter Aortic Valve Implantation
06:59

Improved Registration of 3D CT Angiography with X-ray Fluoroscopy for Image Fusion During Transcatheter Aortic Valve Implantation

Published on: June 3, 2018

Transcatheter aortic valve implantation.

Jian Ye1, Samuel V Lichtenstein

  • 1From the Division of Cardiac Surgery, St. Paul's Hospital, University of British Columbia, Vancouver, Canada.

Innovations (Philadelphia, Pa.)
|March 23, 2012
PubMed
Summary

Catheter-based bioprostheses show promising early results for high-risk patients, with significantly reduced mortality. Long-term durability and expansion to low-risk patients require further investigation.

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Area of Science:

  • Cardiovascular Medicine
  • Medical Devices
  • Interventional Cardiology

Background:

  • Significant advancements in device design and surgical techniques have improved early clinical outcomes for transcatheter aortic valve replacement (TAVR).
  • Two main types of catheter-based bioprostheses, balloon-expandable and self-expandable, are currently used and under investigation.
  • Transarterial and transapical delivery approaches are widely adopted globally.

Purpose of the Study:

  • To review the current status and early clinical outcomes of catheter-based bioprostheses.
  • To discuss the safety and efficacy of transcatheter aortic valve replacement in different patient cohorts.
  • To identify areas for future research in TAVR technology.

Main Methods:

  • Review of recent clinical results and investigations of catheter-based bioprostheses.
  • Analysis of operative mortality rates in high-risk patients undergoing TAVR.
  • Discussion of delivery approaches (transvenous, transarterial, transapical).

Main Results:

  • 30-day operative mortality for TAVR in high-risk patients has significantly decreased to approximately 10%.
  • Recent clinical outcomes are encouraging, demonstrating the promise of these devices.
  • Long-term in vivo durability of catheter-based bioprostheses remains an unknown factor.

Conclusions:

  • Transcatheter aortic valve replacement is a viable option for high-risk patients, with improving outcomes.
  • Caution is advised when considering TAVR for low-risk patients due to the established long-term success of conventional surgery.
  • Ongoing clinical trials are crucial for addressing patient selection, long-term durability, and the overall role of TAVR in valvular disease management.

Related Experiment Videos

Last Updated: May 23, 2026

Improved Registration of 3D CT Angiography with X-ray Fluoroscopy for Image Fusion During Transcatheter Aortic Valve Implantation
06:59

Improved Registration of 3D CT Angiography with X-ray Fluoroscopy for Image Fusion During Transcatheter Aortic Valve Implantation

Published on: June 3, 2018