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Updated: May 23, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
Use of a novel acellular xenograft as a patch for aortic annular enlargement during aortic valve replacement
Marc W Gerdisch1, Akindolapo O Akinwande, Robert G Matheny
1From the *Cardio-Thoracic Surgery, Cardiac Surgery Associates, St. Francis Heart Center, Indianapolis, IN USA; †Meridian Heart Specialists, Indianapolis, IN USA; and ‡CorMatrix Cardiovascular, Alpharetta, GA USA.
Abstract:
A patient with a history of aortic valve endocarditis and surgical debridement presented with acute congestive heart failure because of severe aortic stenosis. During valve replacement surgery, an aortic annular enlargement was required to overcome a potential patient-prosthesis mismatch. We describe the use of a novel, bioresorbable, acellular xenograft for the enlargement patch. This material is expected to remodel into native patient tissue over time. This case offers an alternative implant for left heart reconstruction using a regenerative patch.

