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Multicentric synchronous recurrent aggressive fibromatosis.

Kavita Kohli¹, Vibha Kawatra, Nita Khurana

¹Department of Pathology, Maulana Azad Medical College and Lok Nayak Hospital, Bahadur Shah Zafar Marg, New Delhi, India.

Journal of Cytology

|March 23, 2012

Summary

Recurrent multicentric aggressive fibromatosis (AFM) is rare. This case highlights a young male with synchronous AFM recurrence on the thigh and new lesions on the foot, posing diagnostic challenges.

Keywords:

Aggressive fibromatosis cytology desmoid tumor synchronous multicentric tumors

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Area of Science:

Oncology
Surgical Pathology

Background:

Extra-abdominal desmoid tumors, also known as aggressive fibromatosis (AFM), are rare neoplastic proliferations.
Multicentric and recurrent forms of AFM present diagnostic and management challenges due to their rarity.

Observation:

A young male presented with a thigh mass diagnosed as extra-abdominal fibromatosis.
The patient subsequently developed recurrent swelling at the original site and new lesions on the foot within two months.

Findings:

Histopathology confirmed extra-abdominal fibromatosis.
Fine needle aspiration cytology (FNAC) from all three sites suggested a benign spindle cell lesion of fibrogenic origin, consistent with multicentric synchronous recurrent AFM.

Implications:

This case represents a rare instance of recurrent multicentric, synchronous aggressive fibromatosis.
Highlights the importance of considering multicentricity and recurrence in the diagnosis and management of AFM.
Underscores the utility of FNAC in evaluating suspected recurrent or multifocal fibromatosis.