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Updated: May 23, 2026
04:46
A Modified Transcranial Middle Cerebral Artery Occlusion Model to Study Stroke Outcomes in Aged Mice
Published on: May 5, 2023
Changes in stroke research productivity: A global perspective
Daniel S Chow1, Jason S Hauptman, Tony T Wong
1Department of Radiology, Columbia University, New York Presbyterian Medical Center, New York, NY 10032, USA.
Surgical Neurology International
|March 23, 2012
Summary
Stroke publications show steady worldwide growth, with linear increases in the US and exponential growth in clinical trials. Pain management and rehabilitation specialties are driving this clinical trial expansion.
Area of Science:
- Neurology
- Bibliometrics
- Medical Literature Analysis
Background:
- Stroke is a leading global cause of death.
- Limited quantitative analysis exists for stroke publication trends.
- Understanding publication growth and methodology is crucial for research progress.
Purpose of the Study:
- To quantitatively analyze trends in stroke literature over 12 years (1996-2008).
- To examine changes in worldwide publication productivity.
- To assess shifts in study methodologies within stroke research.
Main Methods:
- Retrospective bibliometric analysis of MEDLINE-indexed stroke articles (1996-2008).
- Data collected included country of origin, methodology, author specialty, and funding sources.
- Linear and nonlinear regression used to analyze growth trends.
Main Results:
- 32,309 stroke articles published; US, Japan, and UK were leading contributors.
- Global and US publications showed linear growth (209.9 and 56.2 articles/year).
- Clinical trials demonstrated exponential growth (7.7% annually), with significant increases from pain management and rehabilitation.
Conclusions:
- Stroke literature exhibits sustained worldwide growth.
- The United States shows continued productivity in stroke research.
- Clinical trial publication is increasing, particularly within pain management and rehabilitation.
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