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MTOR regulates autophagic flux in the glomerulus

Davide P Cinà1, Tuncer Onay, Aarti Paltoo

  • 1Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Ontario Canada.

Autophagy
|March 24, 2012
PubMed
Summary

Sirolimus, an MTOR inhibitor, can cause proteinuria. Researchers studied its role in the glomerular filtration barrier using a mouse model with a specific Mtor gene deletion in podocytes.

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