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Updated: May 23, 2026
05:46
Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation
Published on: January 17, 2019
Uterine fibroid pseudocapsule studied by transmission electron microscopy
Antonio Malvasi1, Carlo Cavallotti, Manrico Morroni
1Department of Obstetrics and Gynaecology, Santa Maria Hospital, Bari, Italy. antoniomalvasi@gmail.com
Summary
The uterine fibroid pseudocapsule, rich in nerves and blood vessels, is actually part of the myometrium. Preserving this smooth muscle layer during fibroid removal is crucial for maintaining uterine integrity.
Area of Science:
- Reproductive biology
- Surgical pathology
- Ultrastructural analysis
Background:
- The uterine fibroid pseudocapsule is a distinct structure surrounding leiomyomas.
- It contains a neurovascular network with neurotransmitters.
- Its precise composition and origin have been debated.
Purpose of the Study:
- To examine the ultrastructural composition of the uterine fibroid pseudocapsule.
- To determine the cellular nature of the pseudocapsule.
Main Methods:
- Transmission electron microscopy was used for ultrastructural analysis.
- Samples were obtained from twenty patients undergoing laparoscopic myomectomy via the intracapsular method.
Main Results:
- Pseudocapsule cells exhibit ultrastructural features consistent with smooth muscle cells.
- The findings indicate that pseudocapsules are an integral part of the myometrium.
Conclusions:
- Uterine fibroid pseudocapsules are composed of myometrial smooth muscle.
- Preserving the pseudocapsule during myomectomy is essential to conserve functional myometrium.
- This practice may help maintain uterine integrity and function post-surgery.
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