Related Experiment Video
Updated: May 23, 2026
08:41
Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
Published on: March 24, 2023
Lower iodine load in routine contrast-enhanced CT: an alternative imaging strategy
Dawn Renae Engelkemier1, Anthony Tadros, Afshin Karimi
1Department of Radiology, University of California, San Diego Medical Center, San Diego, CA, USA.
Journal of Computer Assisted Tomography
|March 27, 2012
Summary
This study shows that a low-volume (15 mL) intravenous contrast protocol for thoracic computed tomography provides adequate imaging quality for many routine thoracic evaluations, reducing contrast administration.
Area of Science:
- Radiology
- Medical Imaging
Background:
- Routine thoracic computed tomography (CT) often utilizes higher intravenous contrast volumes.
- There is a need for alternative imaging strategies to reduce contrast administration.
Purpose of the Study:
- To evaluate the efficacy of a low intravenous contrast volume (15 mL) for routine thoracic CT.
- To determine if this reduced volume provides adequate diagnostic image quality.
Main Methods:
- 61 thoracic CT examinations were performed using 15 mL of iohexol intravenous contrast.
- Image adequacy was retrospectively reviewed by radiologists.
- Vascular enhancement was quantitatively measured and compared to routine protocols.
Main Results:
- All studies were deemed adequate for their intended indications.
- Vascular opacification was sufficient for differentiating mediastinal structures.
- While soft tissue enhancement was reduced, image quality remained diagnostic for key thoracic structures.
Conclusions:
- A 15 mL intravenous contrast protocol is a viable alternative for routine thoracic CT.
- This low-volume strategy yields diagnostic quality images for thoracic inlet, mediastinal, and hilar evaluations.
- Reduced contrast volume can be safely employed in specific patient populations and indications.
Related Concept Videos
01:30Radiological Investigation I: X-ray and CT
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and the...
01:27Imaging Studies III: Computed Tomography
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
01:14Imaging Studies I: CT and MRI
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
01:28Imaging Studies for Cardiovascular System V: CT
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
01:25Imaging Studies II: Positron Emission Tomography and Scintigraphy
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Fundamental Principles of PET
01:26Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...