Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Autism Spectrum Disorder01:19

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
Genetic Screens02:46

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transdisciplinary fetal-neonatal neurology training integrates women's and children's health with life-course brain capital strategies: a narrative review.

Frontiers in neurology·2026
Same author

Anxiety, social responsiveness, and grit among patients with KCNJ11-related neonatal diabetes compared to unaffected siblings.

Acta diabetologica·2026
Same author

An interdisciplinary fetal neonatal neurology collaborative promotes integrative life-course brain health.

Frontiers in neurology·2026
Same author

Hydrocortisone in Preterm Infants and School-Age Functional Outcomes: Follow-Up of a Randomized Clinical Trial.

JAMA pediatrics·2025
Same author

Accounting for social and environmental drivers of neurodevelopment: lessons from a pilot study in a pediatric Colombian cohort.

Pediatric research·2025
Same author

Impact of fine particulate matter air pollution (PM<sub>2·5</sub>) on Nigerian children's performance on tests of cognitive and neurobehavioral development at age seven years.

Environment international·2025
Same journal

Preterm birth: Transition to adulthood.

Developmental disabilities research reviews·2015
Same journal

Kindergarten readiness after prematurity: Integrating health, development, and behavioral functioning to optimize educational outcomes of vulnerable children.

Developmental disabilities research reviews·2015
Same journal

Pathogenesis, neuroimaging and management in children with cerebral palsy born preterm.

Developmental disabilities research reviews·2015
Same journal

Palliative care for extremely premature infants and their families.

Developmental disabilities research reviews·2015
Same journal

Advancing evidence in preterm neonatal medicine.

Developmental disabilities research reviews·2015
Same journal

Preterm birth: An overview of risk factors and obstetrical management.

Developmental disabilities research reviews·2015
See all related articles

Related Experiment Video

Updated: May 23, 2026

Paradigms for Behavioral Assessment in Drosophila Model of Autism Spectrum Disorder
08:30

Paradigms for Behavioral Assessment in Drosophila Model of Autism Spectrum Disorder

Published on: September 6, 2024

Genetic testing for autism spectrum disorders.

Sarah C Bauer1, Michael E Msall

  • 1Northwestern University Feinberg School of Medicine, Department of Pediatrics, Children's Memorial Hospital, Chicago, Illinois 60614, USA. SBauer@childrensmemorial.org

Developmental Disabilities Research Reviews
|March 27, 2012
PubMed
Summary
This summary is machine-generated.

Genetic testing is crucial for diagnosing autism spectrum disorder (ASD) in children. Identifying specific genetic causes can lead to better resources and proactive management of associated conditions.

More Related Videos

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder
09:13

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

Published on: April 22, 2015

Related Experiment Videos

Last Updated: May 23, 2026

Paradigms for Behavioral Assessment in Drosophila Model of Autism Spectrum Disorder
08:30

Paradigms for Behavioral Assessment in Drosophila Model of Autism Spectrum Disorder

Published on: September 6, 2024

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder
09:13

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

Published on: April 22, 2015

Area of Science:

  • Genetics
  • Developmental Pediatrics
  • Neuroscience

Background:

  • Autism spectrum disorder (ASD) presents complex developmental and behavioral phenotypes.
  • While the exact cause of ASD is unknown, genetic factors are strongly implicated.
  • ASD is understood as a multifactorial disorder influenced by both genetic and environmental elements.

Purpose of the Study:

  • To review current genetic testing trends for ASD.
  • To explore potential genetic causes and known genetic disorders linked to ASD.
  • To provide recommendations for genetic testing in ASD evaluations.

Main Methods:

  • Review of current literature on genetic testing for ASD.
  • Analysis of genetic etiologies and associated disorders.
  • Synthesis of recommendations for clinical practice.

Main Results:

  • Genetic testing is a key part of the diagnostic process for children with ASD.
  • Identifying specific etiologies can streamline diagnosis, access resources, and manage comorbidities.
  • Complex genotypes interact with external factors to shape ASD phenotypes.

Conclusions:

  • Genetic testing offers significant benefits for children with ASD, including targeted interventions and reduced diagnostic odyssey.
  • Understanding the genetic underpinnings of ASD is essential for personalized medicine.
  • Access to informed health professionals is vital for effective genetic testing and support for families affected by ASD.