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Updated: May 23, 2026

A Protocol for Measuring Cue Reactivity in a Rat Model of Cocaine Use Disorder
Published on: June 18, 2018
Cost-effectiveness of peer-delivered interventions for cocaine and alcohol abuse among women: a randomized controlled
Jennifer Prah Ruger1, Jennifer Prah Ruger, Arbi Ben Abdallah
1Department of Public Health, Yale University School of Medicine, New Haven, Connecticut, United States of America. jennifer.ruger@yale.edu
Aims:
To determine whether the additional interventions to standard care are cost-effective in addressing cocaine and alcohol abuse at 4 months (4 M) and 12 months (12 M) from baseline.
Method:
We conducted a cost-effectiveness analysis of a randomized controlled trial with three arms: (1) NIDA's Standard intervention (SI); (2) SI plus a Well Woman Exam (WWE); and, (3) SI, WWE, plus four Educational Sessions (4ES).
Results:
To obtain an additional cocaine abstainer, WWE compared to SI cost $7,223 at 4 M and $3,611 at 12 M. Per additional alcohol abstainer, WWE compared to SI cost $3,611 and $7,223 at 4 M and 12 M, respectively. At 12 M, 4ES was dominated (more costly and less effective) by WWE for abstinence outcomes.
Conclusions:
To our knowledge, this is the first cost-effectiveness analysis simultaneously examining cocaine and alcohol abuse in women. Depending on primary outcomes sought and priorities of policy makers, peer-delivered interventions can be a cost-effective way to address the needs of this growing, underserved population.
Trial Registration:
ClinicalTrials.gov NCT01235091.
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