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Updated: May 23, 2026

Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness
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Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness

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Relationship between brachial-ankle pulse wave velocity and cardiovascular risk factors: a multi-ethnic study

En-Zhi Jia1, Feng-Hui An, Pu Liu

  • 1Department of Cardiovascular Medicine, the First Affiliated Hospital of Nanjing Medical University, China.

Internal Medicine (Tokyo, Japan)
|March 28, 2012
PubMed

Insights

Brachial-ankle pulse wave velocity (baPWV) is linked to cardiovascular risks in Chinese adults. Higher age, blood pressure, triglycerides, and cholesterol independently predict increased baPWV, indicating arterial stiffness.

Area of Science:

  • Cardiovascular Health
  • Vascular Biology
  • Public Health

Background:

  • Arterial stiffness, measured by brachial-ankle pulse wave velocity (baPWV), is a marker of cardiovascular risk.
  • Understanding the association between baPWV and cardiovascular risk factors in diverse ethnic populations is crucial for targeted interventions.

Purpose of the Study:

  • To investigate the relationship between brachial-ankle pulse wave velocity (baPWV) and various cardiovascular risk factors in a multi-ethnic Chinese population.
  • To identify independent predictors of elevated baPWV in this cohort.

Main Methods:

  • A cross-sectional study involving 264 adult subjects from diverse ethnic backgrounds in China.
  • Measurements included anthropometrics, baPWV, and laboratory parameters (fasting blood glucose, hemoglobin, erythrocyte count).
  • Statistical analyses included Spearman correlation and multiple regression to assess associations.

Main Results:

  • Significant differences in age, systolic blood pressure, diastolic blood pressure, fasting blood glucose, and hemoglobin were observed across baPWV quartiles.
  • baPWV showed significant positive correlations with age, systolic blood pressure, diastolic blood pressure, and fasting blood glucose.
  • baPWV demonstrated significant negative associations with erythrocyte number and hemoglobin levels.

Conclusions:

  • Age, systolic blood pressure, triglycerides, and cholesterol are independently and positively associated with brachial-ankle pulse wave velocity (baPWV).
  • These findings highlight key modifiable and non-modifiable factors contributing to arterial stiffness in the studied population.
Abstract

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