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Delayed recurrent ischemic stroke after initial good recovery from pneumococcal meningitis
Yuji Kato1, Hidetaka Takeda, Tomohisa Dembo
1Department of Neurology and Cerebrovascular Medicine, Saitama International Medical Center, Saitama Medical University, Japan. yujik@saitama-med.ac.jp
Abstract:
We describe unusual delayed recurrent episodes of ischemic stroke in a patient with initial good recovery from pneumococcal meningitis due to progressive arterial stenosis for over 3 months. We postulate that any of the following may have been responsible for his condition: widespread cerebral vasculopathy due to the effects of purulent material bathing the base of the brain, an immune-mediated para-infectious condition, or a rebound effect of the primary inflammatory reaction that was initially suppressed by dexamethasone. This case demonstrates that progressive arterial stenosis can evolve months after bacterial meningitis and should be recognized as a potential vascular complication.
Insights
Delayed strokes can occur months after pneumococcal meningitis due to progressive arterial stenosis. This rare vascular complication requires recognition following bacterial meningitis recovery.
Area of Science:
- Neurology
- Infectious Diseases
- Vascular Medicine
Background:
- Pneumococcal meningitis can lead to serious neurological complications.
- Early recovery from meningitis does not preclude later vascular events.
Observation:
- A patient experienced delayed, recurrent ischemic strokes over three months post-pneumococcal meningitis.
- Initial recovery from meningitis was good, making the delayed strokes unusual.
Findings:
- Progressive arterial stenosis was identified as the cause of the recurrent ischemic strokes.
- Potential causes include cerebral vasculopathy, immune-mediated conditions, or inflammatory rebound.
Implications:
- Progressive arterial stenosis is a potential, delayed vascular complication of bacterial meningitis.
- Clinicians should consider monitoring for vascular issues months after meningitis recovery.
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